It is mentioned in the Brazilian Pharmacopoeia as a powerful aphrodisiac and has long been used in the Amazon by indigenous peoples for a number of purposes. Natives along the Brazilian Amazon's Rio Negro River use the stems and roots from young plants as a tonic to treat neuromuscular problems. A root decoction is used in baths and massage oils for treating paralysis and beri-beri. A root-and-bark tea is taken to treat sexual dysfunction, rheumatism, grippe, and cardiac and gastrointestinal weakness – it is also valued as a preventive for baldness. In Brazilian herbal medicine, Muira Puama is a highly-regarded sexual stimulant with a reputation as a powerful aphrodisiac.